Multiple Endocrine Neoplasia Type 2 Important
It is possible that the main title of the report Multiple Endocrine Neoplasia Type 2 is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

• MEN-2
• MEN-2 syndrome

Disorder Subdivisions

• familial medullary thyroidcarcinoma (FMTC)
• MEN 2A (Sipple syndrome)
• MEN 2B (multiple neuroma syndrome)
• multiple endocrine neoplasia type 2A
• multiple endocrine neoplasia type 2B
• Wagenmann-Froboese syndrome

General Discussion

Multiple endocrine neoplasia (MEN) type 2 is a rare genetic disorder characterized by an increased risk of developing a specific form of thyroid cancer (medullary thyroid carcinoma) and benign tumors affecting additional glands of the endocrine system. The endocrine system is the network of glands that secrete hormones into the bloodstream where they travel to various areas of the body. These hormones regulate the chemical processes (metabolism) that influence the function of various organs and activities within the body. Hormones are involved in numerous vital processes including regulating heart rate, body temperature and blood pressure. Glands affected in MEN type 2 may secrete excessive amounts of hormones into the bloodstream, which can result in a variety of symptoms.

MEN type 2 is divided into three subtypes: MEN type 2A, MEN type 2B, and familial medullary thyroid carcinoma (FMTC). Medullary thyroid carcinoma (MTC) affects nearly all individuals with MEN type 2 regardless of the subtype. Additional symptoms may occur depending upon the specific subtype present. In FMTC, no other symptoms besides the carcinoma are present. MEN type 2 can run in families or can occur as the result of a spontaneous genetic change (i.e., new mutation) that occurs randomly for no apparent reason.

Resources

American Cancer Society, Inc.
250 Williams NW St
Ste 6000
Atlanta, GA 30303
USA
Tel: (404)320-3333
Tel: (800)227-2345
TDD: (866)228-4327
Internet: http://www.cancer.org

NIH/National Institute of Diabetes, Digestive & Kidney Diseases
Office of Communications & Public Liaison
Bldg 31, Rm 9A06
31 Center Drive, MSC 2560
Bethesda, MD 20892-2560
Tel: (301)496-3583
Email: NDDIC@info.niddk.nih.gov
Internet: http://www2.niddk.nih.gov/

Canadian Multiple Endocrine Neoplasia Society, Inc.
1432 107th Street
North Battleford, S9A 19
Canada
Tel: 3064458436
Fax: 3064458436
Email: hockey_freak99@hotmail.com

Hormone Health Network
8401 Connecticut Avenue
Suite 900
Chevy Chase, MD 20815-5817
Fax: (310)941-0259
Tel: (800)467-6663
Email: hormone@endo-society.org
Internet: http://www.hormone.org/

ThyCa: Thyroid Cancer Survivors' Association, Inc.
PO Box 1545
New York, NY 10159-1545
Fax: (630)604-6078
Tel: (877)588-7904
Email: thyca@thyca.org
Internet: http://www.thyca.org

Association for Multiple Endocrine Neoplasia Disorders (AMEND)
The Warehouse
No. 1 Draper Street
Royal Tunbridge Wells
Kent, TN4 0PG
United Kingdom
Tel: 00441892516076
Fax: 00441892516076
Email: jo.grey@amend.org.uk
Internet: http://www.amend.org.uk

NET Patient Foundation
Boxtrees Farm
The Farm House
Stratford Road
Hockley Heath, B94 6EA
United Kingdom
Tel: 08004346476
Internet: http://www.netpatientfoundation.org

American Multiple Endocrine Neoplasia Support
1027 Hampshire Drive
Maryville, TN 37801
Tel: (865)238-5872
Fax: (865)238-5844
Tel: (866)612-8579
Email: Linda@hagemanfoundation.org
Internet: http://www.amensupport.org

Pheo Para Troopers
P.O. Box 2064
Kokomo, IN 46904
Email: info@pheoparatroopers.org
Internet: http://www.pheoparatroopers.org

Hageman Foundation
1027 Hampshire Drive
Maryville, TN 37801
Tel: (865)238-5842
Fax: (865)238-5844
Tel: (866)612-8579
Email: Info@HagemanFoundation.org
Internet: http://www.HagemanFoundation.org