The Spectrum of Statin Myopathy
Statins are one of the most commonly used agents for treatment of several lipid disorders. As a result, they are used very frequently for prevention and treatment of atherosclerosis and cardiovascular disease. Although they are generally well tolerated, a significant number of patients discontinue their use due to intolerance. Rarely, statins cause a severe and potentially life-threatening myotoxicity leading to rhabdomyolysis and renal failure, which if untreated can result in death.
Toxic Statin Myopathy and Statin Intolerance
Statins are one of the most commonly used agents for treatment of several lipid disorders. As a result, they are used very frequently for prevention and treatment of atherosclerosis and cardiovascular disease. Although they are generally well tolerated, a significant number of patients discontinue their use due to intolerance. Rarely, statins cause a severe and potentially life-threatening myotoxicity leading to rhabdomyolysis and renal failure, which if untreated can result in death.