How to Minimize a Large Blemish Overnight

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    • 1). Wash your face with medicated acne wash according to the package directions. Dry your face with a clean towel, as used towels can hold pimple-causing bacteria.

    • 2). Apply salicylic acid toner. Use a cotton ball for liquid toner or swipe a medicated pad over your face. Allow the toner to dry.

    • 3). Crush a plain aspirin and mix the powder with a few drops of water in the palm of your hand. Alternatively, you can do the same with baking soda. Add only enough water to make a paste and dot a thick coat on your blemish. If you don't have aspirin, apply a drop of calamine lotion or a dab of toothpaste.

    • 4). Wash your face and apply the mixture again, if you wake in the middle of the night.

    • 5). Wash your face the following morning and follow with toner.

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